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标题：Commensal communication to the brain: pathways and behavioral consequences
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作者：John Bienenstock
期刊名称：Microbial Ecology in Health and Disease
印刷版ISSN：1651-2235
出版年度：2012
卷号：23
期号：0
DOI：10.3402/mehd.v23i0.19007
语种：English
出版社：Microbial Ecology in Health and Disease
摘要：In recent years there has been an explosion of investigation of the microbiota which constitutes the gut microbiome. The trillions of bacteria which together make this up are engaged in multiple interactions with each other and the host in which they live. Indeed, they have been regarded as an additional organ within the external compartment of the body which influences the endocrine, metabolic and immune functions of the host. It has only recently received attention from the point of view of influence on the nervous system and this aspect has received the title ‘microbiome-gut-brain axis’. This brief paper highlights some of the recent findings which promote the functional importance of this communication between gut commensals and the enteric and central nervous systems and was part of a lecture given recently at a meeting at the Karolinska Institutet, focused on ‘The Gut and The Brain’, with focus on Autism Spectrum Disorder (ASD).Keywords: probiotics; enteric nervous system; behaviour; autism; brain(Published: 24 August 2012)Citation: Microbial Ecology in Health & Disease 2012, 23: 19007 - http://dx.doi.org/10.3402/mehd.v23i0.19007
关键词：probiotics; enteric nervous system; behaviour; autism; brain