文章基本信息

标题：Cytogenetic Study on the Effect of Bentazon and Glyphosate Herbicide on Mice
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作者：Rania S ; Aboukila ; shabaan A. Hemeda 等
期刊名称：Alexandria Journal of Veterinary Sciences
印刷版ISSN：1110-2047
电子版ISSN：1110-2047
出版年度：2014
卷号：41
期号：1
页码：95-101
DOI：10.5455/ajvs.157875
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出版社：International Medical Journal Management and Indexing System
摘要：Genotoxic effect of acute and chronic doses of Bentazon and Glyphosate herbicides were estimated using micronucleus (MN), nuclear budding, mitotic index (MI) and chromosomal aberration assays. Five groups of Swiss male albino mice were used in acute exposure of 1/5 and 1/10 LD50 of both herbicides after 24, 96 hours of exposure compared to the control. For chronic exposure 1/20 of LD50 of each herbicide was for two months. Genotoxicity of acute doses at different duration of Bentazon and Glyphosate were confirmed through significant increased number of aberrant cells, different types of chromosomal aberration, micronucleus and nuclear budding. Chronic dose of Bentazone induced more genotoxic effects than Glyphosate.
关键词：Genotoxicity; Bentazon; Glyphosate; chromosomal aberrations; micronuclus