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标题：Australian Gonococcal Surveillance Programme annual report, 2012
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作者：Monica M Lahra for the Australian Gonococcal Surveillance Programme
期刊名称：Communicable Diseases Intelligence
印刷版ISSN：1447-4514
电子版ISSN：1445-4866
出版年度：2013
卷号：37
期号：3
页码：E233-E239
出版社：Government Department of Health and Ageing
摘要：The Australian Gonococcal Surveillance Programme has continuously monitored antimi-crobial resistance in clinical isolates of Neisseria gonorrhoeae from all states and territories since 1981. In 2012, 4,718 clinical isolates of gono-cocci from public and private sector sources were tested for in vitro antimicrobial susceptibility by standardised methods. Variation in antibiotic susceptibility patterns were reported between juris-dictions and regions. Resistance to the penicillins and quinolones was high in all jurisdictions except the Northern Territory and Tasmania. Penicillin resistance ranged from 21% in Western Australia to 53% in Victoria. Quinolone resistance ranged from 17% in Queensland to 46% in Victoria, and the resistance was mostly high level. Decreased susceptibility to ceftriaxone (MIC 0.06–0.25 mg/L or greater) was found nationally in 4.4% of isolates, an increase from 3.2% in 2011, but lower than in 2010. To date, there has not been an isolate of N. gonorrhoeae with a ceftriaxone MIC value greater than 0.125 mg/L reported in Australia. Azithromycin susceptibility testing was performed in all jurisdictions and resistance ranged from 0.3% in the Northern Territory to 2.7% in Victoria. The highest reported azithromycin MIC value was 16 mg/L and azithromycin resistant gonococci were not detected in the Australian Capital Territory or Tasmania. Nationally, all isolates remained susceptible to spectinomycin
关键词：antimicrobial resistance; disease ;surveillance; gonococcal infection; Neisseria ;gonorrhoeae