文章基本信息

标题：Influence of Seasonal Variations on In-Vitro Fertilization Success
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作者：Tomić, Jozo ; Tomić, Vlatka
期刊名称：Collegium Antropologicum
印刷版ISSN：0350-6134
出版年度：2011
卷号：35
期号：2
页码：543-546
出版社：Hrvatsko antropološko društvo
摘要：This study was designed to investigate the influence of seasonal variations on the number of retrieved ova, fertilization rate, embryo quality rates and pregnancy rate in IVF cycles. Prospective cohort study was conducted on a total number of 2140 cycles in infertile patients undergoing their first IVF cycle between 2000 and 2007 in IVF policlinic. c2-test, Pearson’s correlation coefficient and one-way analysis of variance were used for statistical analyses. Overall fertilization rate was 77.96% and pregnancy rate 29.15±2.72% per cycle. Seasonal prevalence of pregnancy rate was highest during fall 33.8±4.5% and lowest during summer 23.4±6.2%, but these differences did not reach statistical significance. The study did not show any statistically significant differences in the number of retrieved oocyte, fertilization, and embryo quality according to season. Therefore seasonal changes should not be taken into account in everyday IVF practice.
关键词：assisted reproduction; embryo quality rate; fertilization rate; pregnancy rate; season