文章基本信息

标题：Il nerve growth factor come cura di ulcera cutanea “non-responder” al trapianto di cute
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作者：Marco Aurelio Tuveri(a) ; Viviana Triaca(b) e Luigi Aloe(b)
期刊名称：Annali dell'Istituto Superiore di Sanita
印刷版ISSN：0021-2571
出版年度：2006
卷号：42
期号：01
页码：94-96
出版社：Editrice Kurtis Srl
摘要：(The nerve growth factor induces cutaneous ulcer healing in “non-responder” tranplanted skin). Nerve growth factor (NGF) is an endogenously produced growth factor regulating survival not only of nerve cells, but also of cutaneous tissues. We have recently reported that NGF can promote healing of human corneal ulcer, and cutaneous diabetic and pressure ulcers. In this study, we present a case report showing that NGF can induce recovery of a chronic cutaneous ulcer that failed to respond to all available therapies, including autologous skin transplantation. The result showed that topical application of NGF for 3 consecutive months induced skin ulcer healing and reduced the local inflammation. This finding supports and extents previous studies suggesting the cutaneous healing action and the potential therapeutic role of NGF.
关键词：skin ulcer, NGF treatment, local inflammation, healing action.