文章基本信息

标题：Creatine supplementation spares muscle glycogen during high intensity intermittent exercise in rats
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作者：Hamilton Roschel ; Bruno Gualano ; Marcelo Marquezi 等
期刊名称：Journal of the International Society of Sports Nutrition
电子版ISSN：1550-2783
出版年度：2010
卷号：7
期号：1
页码：6
DOI：10.1186/1550-2783-7-6
语种：English
出版社：BioMed Central
摘要：The effects of creatine (CR) supplementation on glycogen content are still debatable. Thus, due to the current lack of clarity, we investigated the effects of CR supplementation on muscle glycogen content after high intensity intermittent exercise in rats. First, the animals were submitted to a high intensity intermittent maximal swimming exercise protocol to ensure that CR-supplementation was able to delay fatigue (experiment 1). Then, the CR-mediated glycogen sparing effect was examined using a high intensity intermittent sub-maximal exercise test (fixed number of bouts; six bouts of 30-second duration interspersed by two-minute rest interval) (experiment 2). For both experiments, male Wistar rats were given either CR supplementation or placebo (Pl) for 5 days. As expected, CR-supplemented animals were able to exercise for a significant higher number of bouts than Pl. Experiment 2 revealed a higher gastrocnemius glycogen content for the CR vs. the Pl group (33.59%). Additionally, CR animals presented lower blood lactate concentrations throughout the intermittent exercise bouts compared to Pl. No difference was found between groups in soleus glycogen content. The major finding of this study is that CR supplementation was able to spare muscle glycogen during a high intensity intermittent exercise in rats.
关键词：Muscle Glycogen ; Glycogen Content ; Anaerobic Threshold ; Blood Lactate Concentration ; Creatine Supplementation