文章基本信息

标题：Facile Synthesis of Cobalt Oxide Nanoparticle for Biological Studies
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作者：Murugan Perachiselvi ; J. Jenson Samraj ; Muthiah Sakthi Bagavathy 等
期刊名称：Applied Ecology and Environmental Sciences
印刷版ISSN：2328-3912
电子版ISSN：2328-3920
出版年度：2020
卷号：8
期号：5
页码：269-272
DOI：10.12691/aees-8-5-12
出版社：Science and Education Publishing
摘要：Currently Nanoparticles are utilized in various fields and have a different clinical application. In our research, we have developed the Cobalt oxide (Co3O4) NPs using the Sol-gel technique from the Cobalt chloride precursor. The synthesized nanoparticle was characterized by using X-Ray Diffraction (XRD), Scanning Electron Microscope (SEM), Dynamic Light Scattering (DLS), and Fourier Transform Infra-Red Spectroscopy (FTIR). The cytotoxicity studies were evaluated on the Vero cell line (African green monkey kidney cell line) by using MTT assay at 72 hrs. The Cell viability which was observed during the process depends upon the concentration and time exposure. Moreover, the In-vitro cytotoxic effects of Co3O4 NPs showed a better result at the concentration of 50 µg/100µl in Vero cell.
关键词：cobalt oxide NPs; sol-gel technique; MTT assay; cytotoxicity; vero cell line