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标题：FREQUENCY OF ANENCEPHALY AND ITS ASSOCIATED ANOMALIES
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作者：Shilpa K ; Priya Ranganath ; Sumathi S 等
期刊名称：International Journal of Anatomy and Research
印刷版ISSN：2321-4287
出版年度：2018
卷号：6
期号：2
页码：5294-5300
DOI：10.16965/ijar.2018.190
出版社：International Journals of Medical and Health Research
摘要：Introduction: Anencephaly accounts for one of the most common birth defects & is associated with a highmortality & morbidity. The objective was to determine frequency of anencephaly and its associated anomalies,risk factors, clinical presentations & assess maternal awareness on folic acid supplementation and its preventiverole in occurrence of anencephaly.Materials and Methods: The study includes 60 anencephalic fetuses (23 males & 37 females) of 20-30 weeks. Thefetuses were examined for external abnormalities & dissected. Measurements of crown heel, crown rump, headcircumference, foot length, & weight were taken. All the major organs were weighed & data recorded. The sampleswere fixed with 10% buffered formaldehyde. The internal anomalies were noted.Results: The number of deliveries was 57429 deliveries. 23(38.4%) were males & 37(61.6%) were females. Thefrequency of anencephaly in 2014 was 15134/9 (0.06%), in 2015 16361/21 (0.13%). Weight of 40% were 40 yearswere 1.6% & in 36-40 years were 13.4%. Associated anomalies were present in 42 (70%) fetuses. Out of 42fetuses, those who had associated anomalies were 17 (40.4%) males and 25 (59.6%) were females. All the fetuseshad Acrania (100%) & 19 (45.3%) fetuses had spina bifida; there were no anomalies found in reproductivesystem.Conclusion: 4mg of folic acid should be taken before 6 months of conceiving & during the entire pregnancy. Inorder to prevent the anencephaly and associated anomalies certain maternal risk factors should be avoided asprescribed by gynecologist.
关键词：Anencephaly; Crown Heel; Crown Rump; Head Circumference; Foot Length; Weight