文章基本信息

标题：Principles of polymorphism and epistasis for multilocus systems
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作者：Samuel Karlin
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1979
卷号：76
期号：1
页码：541-545
DOI：10.1073/pnas.76.1.541
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：The nature of stable equilibrium configurations is described for general nonepistatic and generalized symmetric viability regimes in multilocus systems under conditions of tight and loose linkage. The influence of epistasis and symmetry can be better understood in terms of these standards. A dichotomy in the nature of stable polymorphisms emerges. More recombination, bisexuality, and multideme interactions facilitate the establishment of central type polymorphisms.
关键词：linkage ; nonepistasis ; symmetric selection ; multilocus Hardy-Weinberg equilibrium ; gametic and allelic polymorphisms