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标题：Changes in Distribution of α-Tocopherol and Cholesterol in Serum Lipoproteins and Tissues of Rats by Dietary PCB and Dietary Level of Protein
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作者：Norihisa KATO ; Yoshiharu MOMOTA ; Tomoko KUSUHARA 等
期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：1989
卷号：35
期号：6
页码：655-660
DOI：10.3177/jnsv.35.655
出版社：Center for Academic Publications Japan
摘要：An experiment was conducted with growing rats to examine the influence of dietary addition of 0.1% polychlorinated biphenyls (PCB) and dietary level of protein on the distributions of α-tocopherol and cholesterol in serum lipoproteins and tissues. Addition of PCB increased serum α-tocopherol. This was mainly due to the increment in the fractions of chylomicrons/very-low-density lipoproteins (VLDL) and high-density lipoproteins (HDL). This chemical also increased serum cholesterol and HDL cholesterol. The contents of α-tocopherol and cholesterol in HDL fraction were higher in the high protein groups as compared to the low protein groups, regardless of PCB intake. PCB intake increased the concentrations of α-tocopherol in tissues including spleen, lung, kidney, testis, muscle, adipose tissue, and brain. High protein diet increased the levels of α-tocopherol in these tissues as compared to low protein diet. PCB intake also increased adrenal α-tocopherol, which was potentiated with low protein diet. The increment in liver α-tocopherol by PCB intake was observed only in the animals fed on low protein diet.
关键词：PCB;dietary protein;serum lipoproteins;α-tocopherol;cholesterol