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  • 标题:Plasma cholesterol lowering action of bile acid binding polymers in experimental animals
  • 本地全文:下载
  • 作者:David M. Tennent ; Henry Siegel ; Mary E. Zanetti
  • 期刊名称:JLR Papers In Press
  • 印刷版ISSN:0022-2275
  • 电子版ISSN:1539-7262
  • 出版年度:1960
  • 卷号:1
  • 期号:5
  • 页码:469-473
  • 语种:English
  • 出版社:American Society for Biochemistry and Molecular Biology
  • 摘要:Feeding of bile acid binding polymeric organic bases inhibited cholesterol rise and aortic. plaque formation in cholesterol-fed cockerels, lowered plasma cholesterol concentrations in normocholesterolemic cockerels and dogs, and increased fecal bile acid and sterol output in a dog. In experiments lasting as long as one year these substances have not produced visible toxic effects. They are thought to act by binding the bile acids in the intestinal tract.
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