摘要:Application of endophytic bacteria can enhance heavy metal removal efficiency of hyperaccumulator plants. These endophytic bacteria can alter metal solubility and facilitate metal accumulation and plant growth. The present study was aimed to isolate endophytic bacteria from roots of Dathura innoxia, growing in heavy metal (HM) contaminated soils and to evaluate their potential to solubilize cadmium (Cd) and promote phytoextraction. Among the eleven isolates, two strains Bacillus cereus and Pseudomonas azotoformans were able to significantly affect Cd bioleaching. Furthermore, resistance capability of these endophytic bacteria was determined by exposing them to 100 mg/l - 400 mg/l Cd solution for various time intervals. Results of study showed that both Bacillus cereus and Pseudomonas azotoformans were able to tolerate 100 mg/l and 200 mg/l of Cd concentration in liquid media. Medicago sativa seedlings grown in artificially contaminated soils with 100 mg/kg and 200 mg/kg of Cd concentration were bioaugmented with ~108 colony-forming units (CFU) per milliliter of bacterial strains to determine their role in growth and uptake of exposed metal. Inoculation of bacterial strains significantly stimulated plant biomass (51 g - 59 g). The study concluded that isolated endophytic bacteria can be utilized effectively for phytoextraction of Cd in nonhost plants as well.